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Bulimia and Cancer: What are the Connections?

Bulimia nervosa (BN) is a serious mental health condition that can contribute to a number of consequences on someone’s physical and emotional well-being. And unfortunately, some studies have shown that one of the physical effects of BN is a higher risk of developing esophageal cancer.

Research into the connection between the two conditions is still ongoing, and some unknowns about the specifics remain. However, what is known is that bulimia nervosa may be an important risk factor for esophageal cancer and numerous other health issues connected to the throat.

Does Bulimia Nervosa Cause Cancer?

Bulimia nervosa may not be a direct cause of cancer, but the additional stress it puts on the body—particularly that caused by self-induced vomiting—could make the body more vulnerable to developing cancerous cells. When found in the lining of the throat, the condition is called squamous cell carcinoma.

Bulimia can make the body more vulnerable to developing cancer.

The repeated presence of stomach acid in the throat can lead to microtrauma in the esophageal mucosa, or essentially tiny tears and other forms of cellular damage. This could eventually lead to issues like gastroesophageal reflux disease, which can further hurt the throat, and chronic physical damage. Similar types of damage have been previously associated with esophageal cancer.

Eating Disorders and Cancer

For people struggling with eating disorders of all types, there are also some factors that may lead to a higher risk of developing cancer.

People with eating disorders tend to be susceptible to substance use disorders, notably those related to smoking and alcohol. These are both noted contributors to cancerous cellular growth. [1]

Eating disorders also tend to lead to chronic nutritional deficiencies, and this has similarly been linked to the development of unhealthy cells or difficulty overcoming illnesses. 

Shared Risk Factors for Eating Disorders and Cancer

One study found a connection between disordered eating behavior and cancer that was strikingly high, with people who were previously hospitalized with an eating disorder having a six-fold increased risk of developing esophageal cancer. [1] However, researchers involved in the study noted some significant limitations of the findings, including a large number of overlapping risk factors between people with eating disorders and people who develop this form of cancer.

Those hospitalized with an eating disorder are 6x more likely to develop esophageal cancer. [1]

Indeed, the study posited that it was these shared risk factors that ultimately posed the greatest risk for people with BN going on to develop esophageal cancer, as opposed to the damage caused to esophageal tissue.

Are People in Recovery at Risk?

It’s difficult to estimate how long someone who has experienced bulimia nervosa or other eating disorders remains at an increased risk for developing esophageal cancer. The outcome depends on incalculable factors, from someone’s genetics and personal health history to the severity of their condition and other risk factors they may experience.

A Case Study

One case study found a woman developed esophageal cancer at 27 years old, nearly 10 years after her struggle with bulimia nervosa. [2] Again, however, lines get blurred when more details are considered. The patient, in this case, had also been a smoker for nearly 7 years and quit only shortly before her cancer diagnosis.

It may be so that chronic bulimia or chronic eating disorders—the terms used to describe more severe cases that last a year or longer—lead to a higher risk of developing cancer later on due to the increased time for microtrauma and severe malnutrition to develop.

Still, lacking further research, it’s unwise and inadvisable to make too many assumptions about why or how BN and other eating disorders can present a greater cancer risk.

Other Health Risks Associated With Bulimia

Unfortunately, esophageal cancer isn’t the only major health risk presented by BN. The condition has been linked to a number of symptoms and potential health consequences, including: [3]

Heart failure

Organ damage

Extreme mood swings

Dry skin

Yellowing skin

Dry and brittle nails

Dental problems

Sleep difficulties

Dizziness

Stomach cramps

Difficulty concentrating

Thinning hair

Muscle weakness

Poor wound healing

Weakened immune system

As BN primarily impacts the digestive system and causes nutritional imbalances in the body, this can cause a cascade of symptoms, which can lead to numerous health issues.

One of the biggest dangers of bulimia nervosa is the potential for a serious electrolyte balance, which can lead to death without any obvious warning signs. Similarly, BN can cause sudden cardiac arrest, which is often also deadly.

When to Get Help for Bulimia Nervosa

If you or a loved one are struggling with bulimia nervosa, it’s important to seek out help as soon as possible. By its very nature, the condition can make a significant impact on your physical and mental health, as well as your quality of life. 

If you’re not sure where to look for help, you can reach out to your physician or a mental health therapist. These trained professionals will be able to offer you advice about the best next steps and point you in the direction of qualified programs. A number of eating disorder hotlines also exist to help people access help and additional resources about these conditions.

Bulimia nervosa is a dangerous and potentially deadly condition, but it doesn’t have to be your destiny. Seeking out treatment can help you get on the path toward a sustained recovery and a happier and healthier future.

Resources

Brewster DH, Nowell SL, & Clark DN. (2015). Risk of Oesophageal Cancer Among Patients Previously Hospitalised with Eating Disorder. Cancer Epidemiology; 39(3):313–320. 

Shinohara ET, Swisher-McClure S, Husson M, Sun W, & Metz JM. (2007). Esophageal Cancer in a Young Woman With Bulimia Nervosa: A Case Report. Journal of Medical Case Reports; 1:160.

Bulimia Nervosa. (2018, February 22). National Eating Disorders Association. Retrieved September 13, 2022.

Harms of diet culture

The Harms of ‘Diet Culture’ & How to Resist 

“Diet culture” has made an increasing mark on society over the years.

While sometimes cloaked in the language of “wellness,” this system of beliefs and social expectations, in fact, revolves around the idea that there exists an “ideal” body type.

Patient and doctor

Medical Complications of Eating Disorders

The specifics of how an eating disorder affects a person is based on any number of individual factors, including the types of eating disorders they’re struggling with, their medical history, and any mental health concerns, among others.

Looking for treatment

Anorexia Hotlines

Eating disorder hotlines can offer a great extension of help for people struggling with these mental health conditions, or those who are looking for eating disorder treatment centers where they can find further help.

Online vs in-person treatment

Online vs. In-Person Treatment for Bulimia

Virtual treatment for bulimia nervosa (BN), or virtual treatment for any mental health disorder, can offer high-quality care. For many people, there isn’t a tangible difference in virtual therapy sessions versus traditional in-person treatment.

Body image

The Impact of Eating Disorders on Body Image

Negative body image and eating disorders are closely related, with negative body image being one of the most well-understood precursors to the development of an eating disorder.

Looking for treatment

Food Addiction Treatment Hotline

Food addiction is an issue we’re only beginning to understand and thoroughly research, but there are a number of resources that can help with this condition and other associated disorders.

LGBTQ group

Anorexia and Bulimia Support Groups

If you’re struggling with an eating disorder or in recovery, you may benefit from an eating disorder support group. There’s a variety of this type of help available, including online support groups and many free options.

Substance use and eating disorders

Eating Disorders With Substance Use Disorder 

Eating disorders and substance use disorders (SUDs) often coexist.

Researchers say up to 50% of people with diagnosed eating disorders use illicit drugs or alcohol, while 35% of people who are dependent on alcohol or drugs have an eating disorder. This represents rates 5 times and 11 times greater than what’s seen in the general population, respectively. [1]

Medications to treat bulimia

Dangers of Medications When Treating Bulimia 

Bulimia nervosa (BN) is a serious mental health condition, marked by periods of binge eating and compensatory purging behaviors, such as self-induced vomiting or excessive exercise.

Inpatient bulimia treatment

Inpatient Treatment for Bulimia: What to Expect 

Many different levels of care can help people struggling with eating disorders, including bulimia nervosa (BN). No type of eating disorder treatment is “better” or “worse,” but rather more well-suited for someone’s particular case.

Eating disorder among people of color

Eating Disorders Among People of Color 

Over the years, certain stereotypes have developed around eating disorders, including the idea that they primarily affect white women and girls. Of course, this isn’t actually the case. Disordered eating behaviors and the negative self-image and poor self-esteem that often drives them impact people of all genders, races, and ages.

Bulimia and alcohol abuse

The Dangers of Bulimia Nervosa and Alcohol Abuse

Many people with one mental health condition will be diagnosed with a comorbid, or co-occurring, disorder. One of the more common comorbid diagnoses is bulimia nervosa (BN) and substance use disorder (SUD).

Food Addiction: A Misleading (and Harmful) Term

As science, medicine, and culture continue to evolve, more attention has been paid to the concept of addiction and the biological and psychological mechanisms that lead to these types of unhelpful, compulsive behaviors.

Choosing the Best Eating Disorder Treatment Centers

If you or a loved one are struggling with an eating disorder, you’ll likely want to enroll in a treatment program as quickly as possible. And while it’s important to get help in a timely manner, some time should be taken to consider the type of treatment facility you choose.

Person looking into the distance

Amenorrhea and Anorexia

Amenorrhea is the absence of menstrual periods in biological women. 

Certain scenarios have been known to naturally bring about this condition, including pregnancy, breastfeeding, certain hormonal contraceptives, and menopause. But sometimes, amenorrhea is a sign of a deeper problem.

Eating disorder statistics

Eating Disorder Statistics & Trends 

Eating disorders affect a small percentage of the overall population, but that still translates to millions of people who are impacted by these conditions. 

And research suggests that many more people silently struggle with an eating disorder without ever being officially diagnosed.

Person with bulimia and substance use disorder

Is Bulimia an Addiction?

Bulimia nervosa (BN) is a mental health condition that manifests as disordered eating behavior. But it can also share many of the same characteristics of drug addiction.

Recent research has found similar connections in the brain that are activated when someone engages in a binging episode and when someone uses recreational drugs.

Healthy body image

Guide to Cultivating a Healthy Body Image 

Negative body image and eating disorders are closely related, with negative body image being one of the most well-understood precursors to the development of an eating disorder.

Eating disorders in the LGBT community

Eating Disorders in the LGBTQ Community 

Eating disorders touch people of all ages, sizes, and orientations. But sadly, some groups, including the LGBTQ+ community, tend to be disproportionately affected by these conditions. 

As a whole, LGBTQ+ people struggle with eating disorders more frequently than those in the hetero-normative community. And many people identifying as LGBTQ+ face multiple treatment barriers.

Sample letter for insurance

Sample Letters to Insurance Companies for Eating Disorder Treatment  

Eating disorder treatment is covered by a large number of insurance policies. But most require families and their doctors to prove that care is needed; sometimes, care teams and insurance administrators disagree about how treatment should work.

Anemia issues from bulimia

Bulimia & Anemia 

Bulimia nervosa (BN) and anemia are often linked, with an estimated overlap rate of more than 11%. [1]

The disordered eating and behavioral patterns associated with bulimia nervosa can cause the body to become deficient in a variety of necessary vitamins and minerals. When the condition leads to a low iron count, it can lead to anemia.

Bulimia and swollen glands

Can Bulimia Cause Swollen Glands?

Bulimia nervosa (BN) can cause a wide range of medical issues, including the swelling of certain glands. Glands in the throat and the face are often particularly impacted.

Bulimia in men and boys

Bulimia Nervosa in Men & Boys

Though people tend to associate eating disorders exclusively with cis-gender women, these conditions impact people of all gender identities, including cis-gender men.

In fact, the number of males diagnosed with an eating disorder jumped up by 70% between 2008 and 2018. [1]

Girl looking at phone

The Impact of Media on Eating Disorders 

A variety of overlapping factors often cause eating disorders. 

And while biological influences account for many of the underlying causes of these conditions, exposure to media can impact body dissatisfaction, increasing the rates of disordered eating and playing a role in the development of an eating disorder. [1]

Bulimia and acid reflux

The Relationship Between Bulimia, Acid Reflux & GERD

While research is ongoing, there have been some studies and reports suggesting a relationship between bulimia nervosa (BN) and acid reflux.

If left untreated, this type of digestive difficulty can eventually lead to gastroesophageal reflux disease (GERD), a fairly serious, chronic condition that can also cause further health complications over time.

Person searching for information

The Effects of Bulimia on the Parotid Gland 

Bulimia can impact the parotid glands, which are salivary glands that serve a number of important purposes. Repeated purging can cause these glands to swell, which can change the shape of the face and potentially cause other health complications.

Pro-ana websites

The Dangers of ‘Pro Ana’ Websites 

Pro-anorexia websites and similar content represent a significant source of potential harm to people struggling with anorexia nervosa (AN) or those at risk of developing it. 

These sources spread dangerous misinformation and can encourage unhealthy ways of viewing one’s own body and the bodies of others.

Effects of bulimia on the throat

The Effects of Bulimia on the Throat

Due to the physical impact of purging, bulimia nervosa (BN) has the potential to cause significant damage to the throat.

These complications can make it hard to talk and painful to swallow. And the repeated behavior can even increase the risk of esophageal cancer, a dangerous and potentially deadly condition.

Person visiting doctor's office

What Bulimia Does to the Mouth 

Bulimia can cause significant damage to a person’s oral health, especially their teeth, mostly as a result of purging. 

And while it’s possible to stop or reverse some of these effects, the longer someone struggles with disordered eating behavior, the more at risk they become for imparting permanent damage.